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Imat (Imatinib) – 100 Mg

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IMAT 100 mg is an oral tablet formulation of imatinib, a selective tyrosine kinase inhibitor (TKI). It is indicated for adult patients with chronic myeloid leukemia (CML), Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL), and c-KIT+ gastrointestinal stromal tumors (GIST). Imatinib targets BCR-ABL, c-KIT, and PDGFR tyrosine kinases, effectively blocking malignant cell growth and disease progression.

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✅ Key Benefits

  • Targets specific kinases (BCR-ABL, c-KIT), reducing cancer cell signaling

  • Oral once-daily dosing offers convenience over IV therapies

  • Proven in clinical trials to achieve high remission rates and durable responses

  • Used in first-line and maintenance therapy across hematologic and solid tumors

  • Well-characterized safety profile allows for long-term use


🎯 How to Use

  • Typically taken as 100 mg once daily, with or without food

  • Swallow whole with a full glass of water

  • Continue treatment until disease progression or intolerable side effects

  • Regular complete blood counts, liver and renal function tests required

  • Adjust dosage in response to side effects or drug interactions


⚠️ Precautions

  • Prescription-only; must be used under oncologist guidance

  • Monitor CBC, liver enzymes, and renal function periodically

  • Risk of fluid retention, hepatotoxicity, and myelosuppression

  • Cardiac monitoring advised—watch for congestive heart failure symptoms

  • Use effective contraception during treatment and for several months afterward

  • Assess concomitant medications for drug interactions


🤕 Possible Side Effects

  • Common: Edema, nausea, muscle cramps, diarrhea, fatigue

  • Blood-related: Neutropenia, thrombocytopenia, anemia

  • Hepatic: Elevated liver enzymes, jaundice (rare)

  • Cardiac: Rare reports of heart failure—seek immediate care for shortness of breath or swelling

  • Other: Skin rash, headache, fever


❓ Frequently Asked Questions (FAQs)

Q. Who is IMAT prescribed for?
A. Patients diagnosed with CML, Ph+ ALL, or c-KIT+ GIST under physician supervision.

Q. How long should therapy continue?
A. It is often continued indefinitely as long as the patient is in remission or tolerates treatment well.

Q. Can IMAT be taken with meals?
A. Yes—taken with or without food; ensure consistent timing each day.

Q. What monitoring is essential?
A. Doctors will monitor blood counts, organ function, and cardiac status regularly to manage safety and efficacy.

Unit

120 Tablets, 150 Tablets, 300 Tablets, 90 Tablets

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