Crizalk (Crizotinib) – 250 Mg

✅ Key Benefits

• Effective against ALK‑positive and ROS1‑positive NSCLC, as well as MET‑exon 14 skipping variant‑driven tumors

• Targets specific oncogenic pathways for personalized treatment

• Crizalk’s 250 mg capsule supports flexible dosing regimens

• Convenient oral therapy option—eliminates need for intravenous infusions

• Used in both treatment‑naïve and previously treated patients with documented mutations

🎯 How to Use

• Recommended dose: one 250 mg capsule twice daily (total 500 mg/day), approximately 12 hours apart

• Swallow capsules whole—avoid crushing or chewing; can be taken with or without food

• Continue until disease progression or unacceptable toxicity

• Dose modifications may be required for side effects (e.g. reduce to 200 mg twice daily, or 250 mg once daily)

• Regular monitoring by oncology team is essential, including imaging and lab tests

⚠️ Precautions

• Prescription-only; not appropriate for individuals without confirmed ALK, ROS1, or MET‑exon 14 skipping mutations

• May cause liver enzyme elevations—frequent liver function tests required, especially during initiation

• QT prolongation is possible—ECG monitoring recommended, especially in patients with risk factors or concomitant QT‑prolonging medications

• Watch for vision issues (diplopia, blurred vision), gastrointestinal symptoms, and edema

• Avoid pregnancy; use effective contraception in both genders during therapy and for a period after discontinuation

🤕 Possible Side Effects

Common:

• Vision disturbances (e.g. light flashes, blurred vision), gastrointestinal upset (nausea, diarrhea, constipation), taste changes, fatigue, peripheral edema

Less common:

• Elevated liver enzymes, mild QT prolongation, dizziness, skin rash, neuropathy

Rare but serious:

• Severe hepatotoxicity, pneumonitis or interstitial lung disease, heart rhythm abnormalities (QT prolongation), bradycardia, severe neutropenia

• Stop treatment and notify your physician if you experience symptoms such as severe shortness of breath, cough, chest pain, dark urine or yellowing skin/eyes, dizziness, or fainting

🎁 Special Offers

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• 🚚 Free shipping on orders over ₹1999 (or equivalent)

• 📦 Discreet, secure packaging and confidential checkout guaranteed

❓ Frequently Asked Questions (FAQs)

Q. Who is Crizalk 250 mg prescribed for?
Patients with ALK‑positive, ROS1‑positive, or MET‑exon 14 skipping variant advanced non‑small cell lung cancer, as confirmed by molecular testing.

Q. What is the standard dosing schedule?
250 mg twice daily—administered approximately every 12 hours, taken continuously until disease progression or intolerable side effects occur.

Q. What if a dose is missed?
Take it as soon as remembered unless it’s near the next scheduled dose; do not double dose. Notify your oncology team if multiple doses are missed.

Q. How are side effects managed?
Dose reductions to 200 mg twice daily or 250 mg once daily may be implemented. Frequent liver tests and ECG monitoring are key to safe use.

Q. Can Crizalk affect vision?
Yes. Transient visual disturbances like blurred vision or flashes of light may occur. Report persistent vision problems to your physician immediately.