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Combutol 800 Mg (Ethambutol)

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Combutol 800 mg delivers a high dose of ethambutol hydrochloride, a bacteriostatic agent essential in tuberculosis treatment. It helps suppress Mycobacterium tuberculosis growth and prevents resistance development when used alongside other first-line TB drugs such as isoniazid, rifampicin, and pyrazinamide. This tablet is intended for adult use and streamlines dosing in weight-based therapy protocols.

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Key Benefits

  • High-strength 800 mg dosage simplifies daily dosing for adult TB treatment

  • Helps prevent drug resistance when combined with other first-line TB medications

  • Oral tablet format supports standard WHO or national tuberculosis treatment protocols

  • Reduces pill burden and supports adherence during intensive-phase therapy

  • Suitable for confirmed TB cases under clinical supervision

🎯 How to Use

  • Administer under medical supervision as part of a multi‑drug TB therapy regimen

  • Dosage is weight-based, typically 15–25 mg/kg once daily, as per treatment guidelines

  • Swallow tablet with water; may be taken with or without food

  • Follow the prescribed schedule precisely; do not alter or skip doses without clinician approval

  • If a dose is missed, take it as soon as possible unless close to the next dose—do not double up and inform your healthcare provider

⚠️ Precautions

  • Prescription-only; must be used as part of supervised TB treatment

  • Baseline and periodic vision testing required—risk of optic neuritis increases with high doses

  • Not advised for patients with pre-existing optic nerve or visual disorders

  • Monitor liver and kidney function, especially when used with other anti-TB medications

  • Vitamin B₆ (pyridoxine) may be co-prescribed if isoniazid is also used to prevent neuropathy

🤕 Possible Side Effects

Common:

  • Blurred vision or difficulty distinguishing colors, gastrointestinal upset, decreased appetite, rash

Less Common:

  • Headache, fatigue, mild elevation of liver enzymes, numbness or tingling in extremities

Rare but Serious:

  • Optic neuritis with potential vision impairment or loss

  • Severe hepatic dysfunction or allergic reactions

  • Seek medical care immediately if experiencing sudden vision changes, jaundice, persistent numbness, or severe abdominal pain

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Frequently Asked Questions (FAQs)

Q. What is Combutol 800 mg used for?
It is indicated for adult TB treatment as part of standard multi-drug regimens to enhance efficacy and simplify dosing.

Q. Can it be used alone?
No. Combutol must be used in combination with other anti-TB medications like rifampicin, isoniazid, and pyrazinamide according to clinical guidelines.

Q. How is vision monitored?
Regular visual acuity testing is mandatory due to the risk of optic neuritis, which can be higher with larger doses.

Q. Why is vitamin B₆ recommended?
Pyridoxine is often co-administered with isoniazid to help prevent neuropathy in multi-drug TB regimens.

Q. What if I miss a dose?
Take it as soon as remembered unless it’s close to your next dose. Do not take two doses in one day, and inform your healthcare provider.

Unit

120 Tablets, 150 Tablets, 300 Tablets, 90 Tablets

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