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Combutol 200 Mg (Ethambutol)

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Combutol 200 mg contains ethambutol hydrochloride, a bacteriostatic agent essential in first-line anti-tuberculosis regimens. It helps prevent resistance and enhances the efficacy of other TB drugs like isoniazid, rifampicin, and pyrazinamide. Used during the intensive phase and continuation phase of TB treatment under medical oversight.

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Key Benefits

  • Essential component in standard anti-tuberculosis therapy

  • Suppresses growth of Mycobacterium tuberculosis and helps prevent resistance

  • Lightweight oral tablet that supports daily dosing

  • Can be used across age groups when dosed appropriately

  • Improves outcomes in pulmonary and extrapulmonary TB when combined with proper multi‑drug regimen

🎯 How to Use

  • Used under direct medical supervision and as part of multi‑drug TB therapy

  • Dosage is weight-based, typically 15–25 mg/kg once daily according to national or WHO guidelines

  • Swallow with water; may be taken with or without food

  • Stick to the prescribed schedule—never alter dosing without physician approval

  • If a dose is missed, take it as soon as remembered if not too close to next dose; do not double up and inform your healthcare provider

⚠️ Precautions

  • Prescription-only; must always be administered as part of a supervised regimen

  • Baseline and periodic vision testing required—risk of optic neuritis increases with dose and duration

  • Not advised in patients with pre-existing optic nerve disorders

  • Monitor liver function and renal status, especially when combined with other anti-TB medications

  • Vitamin B₆ (pyridoxine) may be recommended if using with isoniazid to prevent neuropathy

🤕 Possible Side Effects

Common:

  • Impaired vision (blurred vision or color blindness), gastrointestinal discomfort, decreased appetite, rash

Less Common:

  • Headache, fatigue, elevated liver enzymes, numbness or tingling in hands/feet

Rare but Serious:

  • Optic neuritis—can result in reversible or permanent vision impairment if undetected

  • Signs needing immediate attention: sudden vision changes, yellowish skin/eyes, persistent numbness, significant abdominal pain

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Frequently Asked Questions (FAQs)

Q. What is Combutol 200 mg used for?
It’s used as part of first-line anti-TB drug regimens to treat pulmonary and extrapulmonary tuberculosis under medical supervision.

Q. Should it be taken alone?
No. Combutol must be used in combination with other TB medications (e.g. isoniazid, rifampicin, pyrazinamide) to prevent drug resistance and ensure clinical efficacy.

Q. How is vision monitored?
Baseline and periodic visual acuity tests are required due to ethambutol’s risk of optic neuritis. Report any sudden changes in vision immediately.

Q. Why is vitamin B₆ recommended with TB treatment?
Pyridoxine is often co-prescribed with isoniazid-containing regimens to prevent peripheral neuropathy, especially relevant when using Combutol.

Q. What if I miss a dose?
Take it as soon as you remember unless it’s close to the next dose. Never double up. Notify your healthcare provider if multiple doses are missed.

Unit

120 Tablets, 150 Tablets, 300 Tablets, 90 Tablets

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