Xovoltib 20 Mg (Afatinib Dimaleate)

✅ Key Benefits

• Potent irreversible inhibition of EGFR and HER2-driven tumor signals

• Effective for NSCLC with common and specific uncommon EGFR mutations

• Oral dosing format simplifies long-term administration

• May cross the blood-brain barrier—potentially helpful in patients with brain metastases

• Flexible 20 mg starting dose allows step-wise escalation based on tolerability

🎯 How to Use

• Standard starting dose: one 20 mg tablet taken orally once daily

• Take consistently at the same time, with or without food

• Dose may be increased to 30 mg or 40 mg based on tolerance under medical supervision

• Continue therapy until disease progression or intolerable toxicity

• Monitor skin, gastrointestinal, and liver parameters during treatment

⚠️ Precautions

• Prescription-only; confirm mutation status (EGFR/HER2) before initiating therapy

• May cause diarrhea and skin rash—manage proactively with hydration, antidiarrheals, or topical emollients

• Risk of liver enzyme elevation—periodic liver function tests advised

• May affect heart rhythm or lung function—clinical monitoring recommended

• Not suitable during pregnancy; use proper contraception during and after therapy

🤕 Possible Side Effects

Common (often manageable or dose-dependent):

• Diarrhea, rash or acne-like skin eruptions, mouth sores, nail changes, dry skin, paronychia

Less common:

• Skin pigmentation changes, oral discomfort, mild liver enzyme abnormalities, fatigue

Rare but serious:

• Severe diarrhea leading to dehydration, hepatic dysfunction, lung inflammation (pneumonitis), cardiac effects (e.g. QT prolongation or bradycardia)

• Stop treatment and consult your oncology team if you experience intense abdominal pain, chest discomfort, breathlessness, or yellowing of skin/eyes

🎁 Special Offers

• 💰 Up to 50% OFF sitewide

• 🚚 Free shipping on orders above ₹1999 (or equivalent)

• 📦 Discreet, secure packaging with confidential checkout

❓ Frequently Asked Questions (FAQs)

Q. Who should use Xovoltib 20 mg?
Patients with advanced or metastatic NSCLC harboring activating EGFR mutations, including common (L858R, exon 19 deletion) or select uncommon variants; may also benefit select HER2-positive cases.

Q. Is Xovoltib safe for patients with brain metastases?
It demonstrates activity in the central nervous system; consult your doctor to assess potential benefit based on mutation type and disease spread.

Q. Can the dosage be increased if needed?
Yes—under medical supervision, dose may be escalated to 30 mg or 40 mg daily depending on side effects and tolerance.

Q. What if I miss a dose?
Take it when you remember unless it’s near the next dose. Do not take two doses in one day and consult your healthcare provider for guidance.

Q. How are side effects managed?
Dose reduction or pause may be required; supportive care for diarrhea, skin symptoms, or mouth sores helps maintain therapy. Lab monitoring ensures early detection of serious effects.